Endocrine Abstracts

In the past 20 years or so careful observations in human and rodent diseases of bone metabolism have greatly helped to understand these diseases, but also uncover important pathways in bone metabolism. Such pathways have led to successful drug discovery programmes and some of the latest drugs to be licensed for use in common bone diseases have directly been the result of understanding such ‘experiments of nature’. An example is the targeting of cathepsin K as an anti...